[Faculty] Fwd: [CSRC.COLLOQUIUM] "Protein Adsorption to Surfaces - Insights from Simple Analytical and Computational Models "

[Jose Castillo]

[image: SDSU_CSRC Logo.jpg]


DATE:
*Friday, November 5, 2021*


TITLE:
*Protein Adsorption to Surfaces - Insights from Simple Analytical and
Computational Models*

TIME:
*3:30-4:30PM*



LOCATION:
*In Person - GMCS 314*
or
Join Zoom Meeting -   https://SDSU.zoom.us/j/86808277973
<https://sdsu.zoom.us/j/86808277973>


SPEAKER/BIO:
*Parag Katira, Mechanical Engineering, San Diego State University *



ABSTRACT:

Adsorption of proteins is a critical first step that determines the
response of a biological system to a newly introduced material surface.
Being able to predict and control protein adsorption is then an important
goal in surface engineering for a variety of biomedical applications and
bioengineering applications. Here, using simple computational models, we
try to understand the factors that govern adsorption of proteins to
surfaces. We focus on two key experimental observations - 1) the amount of
time proteins spend on an adsorptive surface, and 2) the adsorption
preventive behavior of surfaces coated with hydrophilic polymers. Many
models of varying complexity have been developed over the last few decades
to explain protein-surface interactions and protein adsorption, however, we
find that most of the experimentally observed phenomena can be captured by
simple analytical or computational models. In this talk, I will present
these data and the models and discuss their implications as well as
shortcomings.


Host:
*Jose Castillo*

Note: Videos of previous colloquium talks can be seen on the CSRC website
in the colloquium archive section or on the CSRC YouTube page here
<https://www.youtube.com/channel/UCN0ZEztlmyDqG2pm-Rle_Eg/feed>.



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