<div dir="ltr"><br clear="all"><div><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><br></div></div></div></div></div></div></div></div><div class="gmail_quote"><br><div dir="ltr"><p style="text-align:center;clear:both"><img src="cid:b4393903-0b84-4e5c-b38c-77aa7b743b39" alt="SDSU_CSRC Logo.jpg" style="margin-left:1em;margin-right:1em"></p><br><div><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;color:rgba(0,0,0,0.87);font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;font-size:14px;text-align:center"><span style="color:black"><font face="verdana, sans-serif"><br><br>DATE:</font></span><font face="verdana, sans-serif"><span style="font-size:10pt;color:black"> </span><span style="font-size:13.5pt;color:black"> <br></span><b><font size="4">Friday, October 16, 2020</font></b></font></p><p class="MsoNormal" align="center" 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style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><span style="font-size:10pt;color:black"></span></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><span style="color:black"></span></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><span style="color:black">TITLE:</span><span style="font-size:10pt;color:black"><br></span></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><span style="font-size:10pt;color:black"></span></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font size="6" face="verdana, sans-serif"></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font size="6" face="verdana, sans-serif"><b><span style="background-image:none;background-position:0% 0%;background-repeat:repeat"></span></b></font></p><div style="text-align:center"><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal"><span style="color:rgb(0,0,0);text-align:left"><font face="verdana, sans-serif" size="4"><b>Structural Puzzles in Virology Solved with an Overarching Icosahedral Design Principle</b></font></span><font face="verdana, sans-serif" size="4"><b> </b></font></p></div><div style="font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><font size="6"><b><br></b></font><font size="6"><b></b></font></font><p class="MsoNormal" style="margin-top:1em;margin-bottom:1em;line-height:normal"><b><font face="verdana, sans-serif"><span style="font-size:11pt;color:black"></span></font></b></p><font face="verdana, sans-serif"><font size="6"><b></b></font><font size="6"><b><span style="font-size:12pt"></span></b></font><font size="6"><b></b></font><font size="6"><b><span style="font-size:11pt"></span></b></font></font></div><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><span style="color:black"></span></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><span style="color:black"></span></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><span style="color:black"><font face="verdana, sans-serif"><br></font></span></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><span style="color:black">TIME:</span><span style="font-size:10pt;color:black"> </span><span style="font-size:13.5pt;color:black"> <br></span><b><font size="4">3:30-4:30PM</font></b></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><br><b><span style="font-size:18pt"><span style="color:black"></span></span></b></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><span style="font-size:10pt;color:black"><font face="verdana, sans-serif"> </font></span></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;text-align:center"><font style="font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif"><span style="color:black">LOCATION:<br></span><font size="4" style="font-weight:bold"><span style="color:black">Join Zoom Meeting - </span></font></font><a href="https://sdsu.zoom.us/j/91071174391" title="https://SDSU.zoom.us/j/91071174391" target="_blank"><font face="verdana, sans-serif" size="4"><b>https://SDSU.zoom.us/j/91071174391</b></font></a><font style="font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif"><font size="4"><font color="#000000"><br></font></font><span style="font-weight:bold"><font size="4"><br></font></span></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><span style="font-size:10pt;color:black"><font face="verdana, sans-serif"> </font></span></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><span style="color:black"></span></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font face="verdana, sans-serif"><span style="color:black">SPEAKER/BIO:</span><span style="font-size:13.5pt;color:black"> </span></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;text-align:center"><font face="verdana, sans-serif" size="4"><b>Dr. Antoni Luque, Mathematics and Statistics, San Diego State University </b></font> <font face="verdana, sans-serif"><br></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><font size="4" face="verdana, sans-serif"><b><b><span style="font-size:18pt"><span style="color:black"></span></span></b></b></font></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><b><font face="verdana, sans-serif"><span style="font-size:18pt"></span></font></b></p><p class="MsoNormal" align="center" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><span style="color:black"><font face="verdana, sans-serif"> </font></span></p><p class="MsoNormal" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif"><font size="2" face="verdana, sans-serif"><span style="color:black"><br></span></font></p><p class="MsoNormal" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif"><font size="2" face="verdana, sans-serif"><span style="color:black"><br></span></font></p><p class="MsoNormal" style="margin-top:1em;margin-bottom:1em;line-height:normal;font-size:14px;font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;text-align:center"><span style="color:black"><font size="2" face="verdana, sans-serif">ABSTRACT:</font></span></p></div><div dir="ltr" style="color:rgba(0,0,0,0.87);font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;font-size:14px"><font face="verdana, sans-serif"><br></font></div><div><div></div></div><div dir="ltr" style="color:rgba(0,0,0,0.87)"><font face="verdana, sans-serif" size="4"><span style="color:rgb(34,34,34)"><br></span></font></div><div dir="ltr" style="color:rgba(0,0,0,0.87)"><span style="color:rgb(0,0,0)"><font face="verdana, sans-serif" size="4">Viruses have evolved protein containers with a wide spectrum of icosahedral architectures to protect their genetic material. The geometric constraints defining these container designs, and their implications for viral evolution, are open problems in virology. The principle of quasi-equivalence is currently used to predict virus architecture, but improved imaging techniques have revealed increasing numbers of viral outliers. In this talk, I will show that this theory is a special case of an overarching design principle for icosahedral, as well as octahedral, architectures that can be formulated in terms of the Archimedean lattices and their duals. These surface structures encompass different blueprints for capsids with the same number of structural proteins, as well as for capsid architectures formed from a combination of minor and major capsid proteins, and are recurrent within viral lineages. They also apply to other icosahedral structures in nature, and offer alternative designs for man-made materials and nanocontainers in bionanotechnology.</font></span><font face="verdana, sans-serif" size="4"><span style="color:rgb(34,34,34)"> </span><span style="color:rgb(34,34,34)"> </span></font><span style="font-family:"Times New Roman",serif;color:rgb(34,34,34)"> </span><font face="verdana, sans-serif" size="4"> </font><font face="verdana, sans-serif" size="4"><br></font><font face="verdana, sans-serif"><br></font></div><div dir="ltr" style="color:rgba(0,0,0,0.87);font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;font-size:14px"><font size="4" face="verdana, sans-serif"> <br></font></div><div dir="ltr" style="color:rgba(0,0,0,0.87);font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;font-size:14px"><font size="4" face="verdana, sans-serif"><br></font><p class="MsoNormal" style="margin:0in 5.2pt 0.0001pt 0in;line-height:13.91px"><font face="verdana, sans-serif"><br></font></p><font size="4" face="verdana, sans-serif"></font></div><font face="verdana, sans-serif" style="font-size:14px"><font size="4"><font color="#000000">Host:</font><font color="rgba(0, 0, 0, 0.870588235294118)"> </font><font color="#000000">Naveen Vaidya</font></font><br></font><div style="color:rgba(0,0,0,0.87);font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;font-size:14px"><font size="4" face="verdana, sans-serif"><br></font></div><div style="color:rgba(0,0,0,0.87);font-family:Roboto,RobotoDraft,Helvetica,Arial,sans-serif;font-size:14px"><p class="MsoNormal" style="margin-top:1em;margin-bottom:1em;line-height:normal"><font face="verdana, sans-serif" size="4"><span style="font-weight:bold">Note:</span><span style="font-weight:bold"> </span>Videos of previous colloquium talks<span style="text-align:center"> can be seen on the CSRC website in the colloquium archive section or on the </span><a href="https://www.youtube.com/channel/UCN0ZEztlmyDqG2pm-Rle_Eg/feed" rel="nofollow" style="color:rgb(26,115,232);text-align:center" target="_blank">CSRC YouTube page here</a><span style="text-align:center">.</span></font></p><p class="MsoNormal" style="margin-top:1em;margin-bottom:1em;line-height:normal"><font face="verdana, sans-serif" size="4"><span style="text-align:center"><br></span></font></p><p class="MsoNormal" style="margin-top:1em;margin-bottom:1em;line-height:normal"><font face="verdana, sans-serif" size="4"><span style="text-align:center"><br></span></font></p><p class="MsoNormal" style="margin-top:1em;margin-bottom:1em;line-height:normal"><font face="verdana, sans-serif" size="4"><span style="text-align:center"><br></span></font></p></div></div></div>
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