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<div style="margin:0px;padding:0px;text-align:center;font-family:Verdana;font-size:10pt;color:#000000"><div style="text-align:center;font-family:Verdana;font-size:10pt;color:#000000"><div style="padding:20px 20px"><div id="m_4717692223985506136divHostedEmailLink"><a href="http://emclick.imodules.com/wf/click?upn=5IGwUT6rZYuEEGfjd43m3ge8JO-2BKeD9yKvE8M5FqYO6w5H6dGIizUvO-2BKuhhQhxIl7FUnKo8L-2F5uIIeAMJpWD4at1vCwufA6q8uIDsMotJaD-2FPCShTgW-2Ffsg-2BHze0dTtpJdO6iQELxZVT88b1lUWV8kUQratjRHopi0LH4A6Ww0-3D_2e1wJIZhuboB7dJTSS9NwpRwMMT2ePhLv5uM0c6Ol6XrlT5zfuHryH-2FAThT2XlAkn-2BBzAUHbAg3xRbUE3XoVlsxv2ALidoUOoUF4COxGd1QYyuGTFFryH7slvqaFuWD2d94uVLWKDLX-2ByPIXJOk-2F1a8InMjujjIm8-2BX9SDHX2q9TdXiPlGDmvVvlvFburPYejGS0oQjaD-2BTs02rgsEzNVxRjbfAjGaqPkMU-2B-2BJPp11IhZGWy7tjpATyuLIoPHdf-2FPAvToscJFPkMZHNxr7PaMt-2FouH-2BQtd-2B-2BNjae7-2BbbaM-2BJyX1yx1AMMJJSeP3TmNDqdHHqSsFyPXv8QQMyBbqiUlVQlrs21T2U5tkqx5xR2fiTYmYs9tGiNQGATvanZiKBx4QKlZwdBWhd3Zu-2BEzLNZR9KZ9qwBD5p-2Bb1TLVbPqM5jnW-2Fx7zA2uj1sydXJPYuR" target="_blank">View this email in a web page</a></div>
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<td colspan="2"><div style="clear:both"><div><p align="center"> <img src="http://www.sdsualumni.org/s/997/images/editor/csrc-alumni/csrcbanner_jpg.jpg" alt="" width="1017" height="115"><br> </p></div></div><div style="clear:both"><div><p align="center"><span style="font-family:Verdana,sans-serif;color:black">DATE:</span><span style="font-size:10pt;font-family:Verdana,sans-serif;color:black"> </span><span style="font-family:Verdana,sans-serif;font-size:18px;color:black"> <strong><span style="font-family:Verdana,sans-serif">Friday, September 22, 2017</span></strong></span></p> <p align="center"><span style="font-size:10pt;font-family:Verdana,sans-serif;color:black"> </span></p> <p align="center"><span style="font-family:Verdana,sans-serif;color:black">TITLE:</span><span style="font-size:10pt;font-family:Verdana,sans-serif;color:black"> </span><strong><span style="font-size:13.5pt;font-family:Verdana,sans-serif;color:black">Whole Genome Sequencing in the Clinic<br> </span></strong></p> <p align="center"><span style="font-size:10pt;font-family:Verdana,sans-serif;color:black"> </span></p> <p align="center"><span style="font-family:Verdana,sans-serif;color:black">TIME:</span><span style="font-size:10pt;font-family:Verdana,sans-serif;color:black"> </span><span style="font-family:Verdana,sans-serif;font-size:18px;color:black"> <strong><span style="font-family:Verdana,sans-serif">3:30PM</span></strong></span></p> <p align="center"><span style="font-size:10pt;font-family:Verdana,sans-serif;color:black"> </span></p> <p align="center"><span style="font-family:Verdana,sans-serif;color:black">LOCATION:</span><span style="font-size:10pt;font-family:Verdana,sans-serif;color:black"> <strong><span style="font-family:Verdana,sans-serif"> </span></strong></span><span style="font-size:18px"><strong><span style="font-family:Verdana,sans-serif;color:black">GMCS 314</span></strong></span></p> <p align="center"><span style="font-size:10pt;font-family:Verdana,sans-serif;color:black"> </span></p> <p align="center"><span style="font-family:Verdana,sans-serif;color:black">SPEAKER:</span><span style="font-family:Verdana,sans-serif;font-size:18px;color:black"> <strong>Dr. Semyon Kruglyak, Director, Illumina, Inc.<br> </strong></span></p> <p align="center"><span style="font-size:16px"><br> <em></em></span></p> <p align="center"><span style="font-family:Verdana,sans-serif;font-size:18px;color:black"><strong> </strong></span><strong></strong></p> <p><span style="font-size:10pt;font-family:Verdana,sans-serif;color:black"> </span></p> <p><span style="font-family:Verdana,sans-serif;color:black">ABSTRACT:</span></p> <p><span style="font-size:11pt;font-family:Verdana,sans-serif">Rare and undiagnosed diseases cause great suffering to affected families and create a disproportionate burden on the health system. A promising approach to ending the diagnostic odyssey of the patient is to utilize whole genome sequencing as a first line test for rare, genetic disease. In this talk, I will describe the methods utilized in creating such a test, with a focus on variant calling. I will then describe how these methods are used in practice.</span></p> <p><br> </p> <p><br> </p> <p><span style="font-size:9.5pt;font-family:Verdana,sans-serif;color:black"> </span></p> <p><span style="font-size:9.5pt;font-family:Verdana,sans-serif;color:black">HOST: <strong>Jose Castillo<span style="font-family:Verdana,sans-serif"><br> </span></strong></span></p> <p><span style="font-size:9.5pt;font-family:Verdana,sans-serif;color:black"> </span></p> <p><span style="font-size:9.5pt;font-family:Verdana,sans-serif;color:black">Dr. Jose E. Castillo<br> Director/Professor<br> Computational Science Research Center<br> <a href="https://maps.google.com/?q=5500+Campanile+Drive+San+Diego&entry=gmail&source=g">5500 Campanile Drive</a><br> <a href="https://maps.google.com/?q=5500+Campanile+Drive+San+Diego&entry=gmail&source=g">San Diego</a> State University<br> San Diego, CA 92182-1245<br> (619) 59407205/3430, FAX <a href="tel:(619)%20594-2459" value="+16195942459" target="_blank">(619) 594-2459</a></span></p> <p><br> </p></div></div></td>
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<p style="padding:3px;font-size:10px;color:#999999;font-family:verdana;text-align:center">San Diego State University<br>
<a href="https://maps.google.com/?q=5500+Campanile+Drive+%0D+San+Diego+CA+92182&entry=gmail&source=g">5500 Campanile Drive</a><br>
San Diego CA 92182<br>
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</div><br><br clear="all"><div><br></div>-- <br><div class="gmail_signature" data-smartmail="gmail_signature">
<p>Jose E. Castillo Ph.D.</p><p>Director / Professor </p>
<p>Computational Science Research Center</p>
<p>5500 Campanile Dr</p>
<p>San Diego State University</p>
<p>San Diego CA 92182-1245</p>
<p>619 5947205/3430, Fax 619-594-2459</p><p> <a href="http://www.csrc.sdsu.edu/mimetic-book/" target="_blank">http://www.csrc.sdsu.edu/mimetic-book/</a></p></div>
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