[Faculty] Fwd: [CSRC.COLLOQUIUM] "Escaping the Stiffness Trap: The Unlikely Journey of Metastatic Cancer Cells"

[Jose Castillo]

[image: SDSU_CSRC Logo.jpg]




DATE:
*Friday, July 10, 2020*



TITLE:

*Escaping the Stiffness Trap: The Unlikely Journey of Metastatic Cancer
Cells*


TIME:
*3:00-4:00PM*




LOCATION:
Join Zoom Meeting -  *https://SDSU.zoom.us/j/96847180420*
<https://sdsu.zoom.us/j/96847180420>



SPEAKER/BIO:

*Dr. Parag Katira, Mechanical Engineering, San Diego State University*





ABSTRACT:

Experiments have shown that most adherent cells, including cancer cells,
can sense the stiffness of their environments and tend to migrate towards
regions of high stiffness when a stiffness gradient is present. This
migration of cells up a stiffness gradient is called durotaxis. However, in
most solid tumors, such as those of the lungs, pancreas, breast, ovaries,
kidneys and so on, the tissue environment immediately surrounding a tumor
is stiffer compared to the healthier tissue further away. One would expect
this would make it harder for tumor cells to escape the primary tumor to
migrate into healthier tissue and form secondary metastasis. And yet, this
is a common occurrence in aggressive cancers. What, then, drives the
migration of metastatic cancer cells against a stiffness gradient?




Host: Jose Castillo

Note: Videos of previous colloquium talks can be seen on the CSRC website
in the colloquium archive section or on the CSRC YouTube page here
<https://www.youtube.com/channel/UCN0ZEztlmyDqG2pm-Rle_Eg/feed>.

-- 
You received this message because you are subscribed to the Google Groups
"CSRC Colloquium" group.
To unsubscribe from this group and stop receiving emails from it, send an
email to csrc.colloquium+unsubscribe at sdsu.edu.
To view this discussion on the web visit
https://groups.google.com/a/sdsu.edu/d/msgid/csrc.colloquium/be1ba26a-899f-489d-bb20-122e9053f7d4o%40sdsu.edu
<https://groups.google.com/a/sdsu.edu/d/msgid/csrc.colloquium/be1ba26a-899f-489d-bb20-122e9053f7d4o%40sdsu.edu?utm_medium=email&utm_source=footer>
.
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://engineering.sdsu.edu/pipermail/faculty/attachments/20200706/87500b58/attachment-0001.html>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: SDSU_CSRC Logo.jpg
Type: image/jpeg
Size: 17493 bytes
Desc: not available
URL: <http://engineering.sdsu.edu/pipermail/faculty/attachments/20200706/87500b58/attachment-0001.jpg>