[Faculty] Fwd: [CSRC-SDSU COLLOQUIUM]: "An Information Theoretic Approach for Computing Spatial Heat Maps from Time Series Data"
Jose Castillo
jcastillo at mail.sdsu.edu
Tue Nov 28 14:57:32 PST 2017
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DATE: *Friday, December 1, 2017*
TITLE:
*An Information Theoretic Approach for Computing Spatial HeatMaps from Time
Series Data*
TIME: *3:30PM*
LOCATION: *GMCS 314*
SPEAKER:
*Willy Wriggers, Ph.D, Department of Mechanical & Aerospace
Engineeringand Institute of Biomedical EngineeringOld Dominion University,
Norfolk, VA*
ABSTRACT:
We are developing statistical analytics for generating spatial heat maps
that visualize the importance of local channel recordings to global
processes. The maps are created by information matching of fast and slow
degrees of freedom arising in the highly resolved time series data. We are
currently applying this technology to diverse research fields, for example
to the mapping of spoken language production and perception patterns in the
human brain. The heat maps locate time-dependent patterns on the brain of
epilepsy patients who had an intracranial EEG electrode arrays implanted on
the cortex. The analytics is also applied to the detection of biochemically
relevant activity centers in molecular dynamics computer simulations of
atomic protein structures. Our novel Balanced Adaptive Density Estimation
(BADE) approach solves the general problem of how to efficiently estimate
the probability density function of very unevenly sampled random variables
arising in our mutual information calculations. Since the method is of
general applicability, we expect our heat map technology to be generally
useful for applications in all scientific and engineering application
domains where time-dependent signals should be transformed to spatial maps,
such as in geophysics, signal processing and econometrics. BADE is freely
distributed with our TimeScapes analytics package at URL
http://timescapes.biomachina.org.
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BIO:
Dr. Wriggers earned a Ph.D. in Physics from the University of
Illinois, Urbana-Champaign in 1998. He held postdoctoral positions in
Electron Microscopy (Scripps Research Institute) as well as
Theoretical Chemistry (University of California, San Diego). In 1999
he was appointed Assistant Professor at The Scripps Research
Institute. In 2003, he moved to the University of Texas Health Science
Center, Houston, where he earned tenure as Associate Professor of
Biomedical Informatics and Molecular Medicine. In 2007 he joined the
private D. E. Shaw Research laboratory in New York City, where he
participated in the historic millisecond length molecular dynamics
simulation on the *Anton* special purpose supercomputer. In 2014, he
returned to an academic position as Frank Batten Professor in
Mechanical and Aerospace Engineering at ODU.
HOST: Thomas Rockwell
Dr. Jose E. Castillo
Director/Professor
Computational Science Research Center
5500 Campanile Drive
San Diego State University
San Diego, CA 92182-1245
(619) 59407205/3430, FAX (619) 594-2459
_______________________________________________
SDSU Computational Science Research Center
Mailing List
--
Jose E. Castillo Ph.D.
Director / Professor
Computational Science Research Center
5500 Campanile Dr
San Diego State University
San Diego CA 92182-1245
619 5947205/3430, Fax 619-594-2459
http://www.csrc.sdsu.edu/mimetic-book/
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